Selected article for: "normal reference range and reference range"
Title: 2016 ACVIM Forum Research Abstract Program
  • Document date: 2016_5_31
    • ID: 2y1y8jpx_702
    Snippet: At initial examination, the most common clinical signs at initial diagnosis were regional hypertrichosis (9/16), delayed shedding (5/16) and muscle wasting (4/16). The baseline (arithmetic mean) for T0ACTH and T10ACTH for all horses was 44.6 pg/mL and 360.5 pg/mL, respectively. Following six-months of treatment, the resting T0ACTH in 12 of 16 (75%) horses were less than normal reference range (35 pg/mL), whereas 7 of 16 (44%) of horses had T10ACT.....
    Document: At initial examination, the most common clinical signs at initial diagnosis were regional hypertrichosis (9/16), delayed shedding (5/16) and muscle wasting (4/16). The baseline (arithmetic mean) for T0ACTH and T10ACTH for all horses was 44.6 pg/mL and 360.5 pg/mL, respectively. Following six-months of treatment, the resting T0ACTH in 12 of 16 (75%) horses were less than normal reference range (35 pg/mL), whereas 7 of 16 (44%) of horses had T10ACTH less than the recommended T10ACTH reference range (110 pg/mL). In June, the decrease from baseline for T0ACTH was 7.1%; whereas the decrease from baseline for T10ACTH was 49.1%. All horses with regional hypertrichosis and delayed shedding were considered improved or resolved, whereas body condition and muscle wasting was slightly improved. Four adverse events not related to treatment were reported and considered resolved within 24 hours.

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