Author: Pandya, Gagan A.; Holmes, Michael H.; Sunkara, Sirisha; Sparks, Andrew; Bai, Yun; Verratti, Kathleen; Saeed, Kelly; Venepally, Pratap; Jarrahi, Behnam; Fleischmann, Robert D.; Peterson, Scott N.
Title: A bioinformatic filter for improved base-call accuracy and polymorphism detection using the Affymetrix GeneChip® whole-genome resequencing platform Document date: 2007_11_15
ID: 16tii0ha_17
Snippet: The availability of a published complete genome sequence for the SCHU S4 strain allowed us to predict the set of expected SNP calls that should occur as the result of hybridizing the SCHU S4 sample to the LVS portion of the chip set. Consequently, we were able to characterize the SNP calls resulting from these experiments as either true positives or false positives. We used this information to parameterize and validate our filter algorithms......
Document: The availability of a published complete genome sequence for the SCHU S4 strain allowed us to predict the set of expected SNP calls that should occur as the result of hybridizing the SCHU S4 sample to the LVS portion of the chip set. Consequently, we were able to characterize the SNP calls resulting from these experiments as either true positives or false positives. We used this information to parameterize and validate our filter algorithms.
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