Selected article for: "class astrocytes expression and cns disease"
Title: Coronavirus induction of class I major histocompatibility complex expression in murine astrocytes is virus strain specific
  • Document date: 1994_9_1
    • ID: 4bf8eiix_33
    Snippet: In conclusion, we present data indicating that significant differences exist among MHV strains in their ability to stimulate class I expression in murine astrocytes, and that these differences may contribute to their ability to cause CNS disease. Since class I expression has been reported on astrocytes in the brains of MS patients (77) , the data have implications for understanding the role of class I in human CNS disease......
    Document: In conclusion, we present data indicating that significant differences exist among MHV strains in their ability to stimulate class I expression in murine astrocytes, and that these differences may contribute to their ability to cause CNS disease. Since class I expression has been reported on astrocytes in the brains of MS patients (77) , the data have implications for understanding the role of class I in human CNS disease.

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