Selected article for: "AUC curve area and maximum concentration"

Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018
  • Document date: 2018_10_25
  • ID: 60ceejq1_103
    Snippet: Changes in glucose and insulin concentration at each time point, area under the curve (AUC), maximum concentration (C max ), and time at C max (T max ) were compared between formulations using a two way analysis of variance with repeated measures. Bland Altman analysis was used to determine agreement in insulin concentrations between formulations. There were no significant differences between Karo and Crown syrup formulations at any individual ti.....
    Document: Changes in glucose and insulin concentration at each time point, area under the curve (AUC), maximum concentration (C max ), and time at C max (T max ) were compared between formulations using a two way analysis of variance with repeated measures. Bland Altman analysis was used to determine agreement in insulin concentrations between formulations. There were no significant differences between Karo and Crown syrup formulations at any individual time points for insulin or glucose concentrations in either experiment (P > 0.2) There were no significant differences between the area under the curve, T max , or C max for insulin or glucose concentrations with Karo compared to Crown syrup (P > 0.1). Bland-Altman analysis of insulin concentrations indicated a mean bias (Karo-Crown) of 4 μIU/mL (95% limits of agreement, −11.7 to 19.6 μIU/mL; experiment 1) or a mean bias of 1.6 μIU/ml (95% limits of agreement, −11 to 14.2 μIU/ml; experiment 2) for insulin concentrations at 75 minutes. This study suggests that horses have similar glucose and insulin responses to these two formulations of corn syrup.

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