Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018 Document date: 2018_10_25
ID: 60ceejq1_164
Snippet: This study demonstrated the safety of acetaminophen with repeated oral dosing over 14 days. This study also confirms that the 20 mg/kg dose used in previous clinical reports reaches proposed therapeutic concentrations after oral administration to fed horses, however a shorter 6-8 hour dosage interval may be required for improved efficacy. heart rate was detected. This study identified that dexmedetomidine was rapidly but incompletely absorbed aft.....
Document: This study demonstrated the safety of acetaminophen with repeated oral dosing over 14 days. This study also confirms that the 20 mg/kg dose used in previous clinical reports reaches proposed therapeutic concentrations after oral administration to fed horses, however a shorter 6-8 hour dosage interval may be required for improved efficacy. heart rate was detected. This study identified that dexmedetomidine was rapidly but incompletely absorbed after subcutaneous administration. Higher plasma concentrations after intravenous administration were associated with increased blood pressure, compared with subcutaneous administration. These results suggest a need for dosage adjustment based on route of administration for dexmedetomidine.
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