2015 ACVIM Forum Research Abstract Program

Two hundred and eleven treatments performed on 40 dogs were found to fit the inclusion criteria. Statistically significant correlations were found between the D-PNa and change in post dialysis PNa, the DNa and the final PNa, and the starting D-PNa to final D-PNa. The initial D-PNa had the strongest correlation to the observed change in patient sodium; the predicted change in PNa is predicted by 0.73 * D-PNa -5.83 (regression coefficient = 0.73, 95%CI: 0.67-0.79, r 2 = 0.72, P < 0.0001). The DNa was moderately correlated with the final PNa (regression coefficient = 0.76, 95%CI: 0.66-0.86, r 2 = 0.50, P < 0.0001). The initial D-PNa had the weakest correlation to the final D-PNa (regression coefficient = 0.27, 95%CI: 0.21-0.33, r 2 = 0.27, P < 0.0001). A 1 mmol D-PNa gradient should produce 0.73 mmol change in PNa over the course of the dialysis treatment.