Author: Ma, Lili; Du, Hongmei; Chen, Guangdong
Title: Differential network as an indicator of osteoporosis with network entropy Document date: 2018_5_16
ID: 61t686w7_6
Snippet: Datasets and construction of PPINs. One biological data set E-GEOD-7158 of osteoporosis was derived from the Gene Expression Omnibus (GEO) database (http://www.ncbi.nlm. nih.gov/geo/) (3). There were 12 monocyte low PBM samples and 11 high PBM samples in the total 23 samples. The platform is A-AFFY-44-Affymetrix GeneChip Human Genome U133 Plus 2.0 (HG-U133 Plus 2.0). The Linear Models for Microarray Data (LIMMA) was then used to preprocess data. .....
Document: Datasets and construction of PPINs. One biological data set E-GEOD-7158 of osteoporosis was derived from the Gene Expression Omnibus (GEO) database (http://www.ncbi.nlm. nih.gov/geo/) (3). There were 12 monocyte low PBM samples and 11 high PBM samples in the total 23 samples. The platform is A-AFFY-44-Affymetrix GeneChip Human Genome U133 Plus 2.0 (HG-U133 Plus 2.0). The Linear Models for Microarray Data (LIMMA) was then used to preprocess data. After quantile data normalization performed by robust multi-array average (RMA) (21), 20,545 genes were obtained.
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