Author: Ivanova, Elena; Berger, Audrey; Scherrer, Anne; Alkalaeva, Elena; Strub, Katharina
Title: Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits Document date: 2015_3_11
ID: 64cnoqpi_44
Snippet: To determine whether Alu RNPs could also block IRESmediated translation initiation, we made reporter constructs containing IRES sequences from the hepatitis C virus (HCV) and the cricket paralysis virus (CrPV) upstream of Fluc. Formation of the 48S complex on HCV IRES is dependent on eIF3 and either eIF2/eIF5 or eIF5B, whereas the CrPV IRES directly recruits the 40S subunit to the start codon without the need for initiation factors (22) ......
Document: To determine whether Alu RNPs could also block IRESmediated translation initiation, we made reporter constructs containing IRES sequences from the hepatitis C virus (HCV) and the cricket paralysis virus (CrPV) upstream of Fluc. Formation of the 48S complex on HCV IRES is dependent on eIF3 and either eIF2/eIF5 or eIF5B, whereas the CrPV IRES directly recruits the 40S subunit to the start codon without the need for initiation factors (22) .
Search related documents:
Co phrase search for related documents- Alu rnp and translation initiation: 1, 2, 3, 4, 5
- cricket paralysis virus and paralysis virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- cricket paralysis virus and translation initiation: 1, 2
- initiation factor and translation initiation: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- ires sequence and reporter construct: 1
- ires sequence and translation initiation: 1, 2, 3, 4
- paralysis virus and translation initiation: 1, 2
Co phrase search for related documents, hyperlinks ordered by date