Author: Ivanova, Elena; Berger, Audrey; Scherrer, Anne; Alkalaeva, Elena; Strub, Katharina
Title: Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits Document date: 2015_3_11
ID: 64cnoqpi_46
Snippet: We also performed 48S complex assembly on CrPV-VHLM (see Supplementary Methods) and the HCV-NS' (23) mRNAs containing the HCV and the CrPV IRES, respectively. In both cases, 48S complex formation was specifically inhibited by the scAluY A RNP whereas the SA110 RNP and the scAluY A 14A5 RNP, the negative controls, did not significantly reduce the formation of 48S initiation complexes ( Figure 4C and D) ......
Document: We also performed 48S complex assembly on CrPV-VHLM (see Supplementary Methods) and the HCV-NS' (23) mRNAs containing the HCV and the CrPV IRES, respectively. In both cases, 48S complex formation was specifically inhibited by the scAluY A RNP whereas the SA110 RNP and the scAluY A 14A5 RNP, the negative controls, did not significantly reduce the formation of 48S initiation complexes ( Figure 4C and D) .
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