Assessing health burden risk and control effect on dengue fever infection in the southern region of Taiwan

Cheng, Yi-Hsien; Lin, Yi-Jun; Chen, Szu-Chieh; You, Shu-Han; Chen, Wei-Yu; Hsieh, Nan-Hung; Yang, Ying-Fei; Liao, Chung-Min

This study provides an integrated dengue-mosquito-human transmission model and explores the temperature-R 0 -DALYs relationship for disease burden of dengue fever in southern Taiwan. In the absence of detailed and robust surveillance data, our presented modeling framework provides a useful tool to measure dengue health burden risk and to quantify the effect of dengue control on A. aegypti infection prevalence and disease incidence in the southern region of Taiwan. Most importantly, we quantified the various control interventions to simulate the optimal containment in different seasons. These results are useful to provide the reference to understand the temperature-associated dengue prevalence and to identify priority interventions for high dengue burden regions.