2015 ACVIM Forum Research Abstract Program

The objectives of this study were to describe a population of spayed female dogs with USMI and investigate their initial presentation, diagnosis, and treatment. Information was collected on 205 dogs with USMI (UI) diagnosed between January 2009 and December 2012, and 197 continent neutered female dogs (C). Neither age nor BCS differed between groups. UI dogs weighed more than C dogs (P = 0.001). There was no significant difference in age at neuter between UI dogs and C dogs, however, for every 3 months delay in neutering during the first year of life, USMI risk declined (P = 0.038). Median time from neuter to UI signs was 3.43 years, and from first signs to veterinary consult was 21 days. 85.7% of dogs were diagnosed with USMI at initial presentation. Phenylpropanolamine (PPA) was prescribed in 77.45%, diethylstilbestrol in 19.61%, and combination therapy in 2.94% of dogs. This data supports previous studies showing heavier dogs have increased risk for USMI and that its onset occurs within a few years of neuter. Risk association with age at neuter remains controversial. Owners appear likely to seek veterinary care relatively soon after the onset of clinical signs, and in most cases diagnosis of USMI is prompt. Treatment choices may reflect the differences in availability of PPA and estrogenic compounds during the period studied. Viyo is a nutritional supplement that may increase appetite and water consumption. This pilot study evaluated effects of Viyo Recuperation TM -Renal (VRR) on biochemical parameters in cats with chronic kidney disease (CKD) and compared palatability in CKD cats with normal appetites versus CKD cats with decreased appetites.