Selected article for: "bacterial taxa and LEfSe analysis"
Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018
  • Document date: 2018_10_25
    • ID: 60ceejq1_332
    Snippet: Ten diabetic dogs and 10 healthy controls were enrolled. Fecal microbial diversity was lower in DM dogs when compared to healthy controls. PCA based on unweighted Unifrac distance metric did not reveal significant clustering between dog groups. However, linear discriminate analysis effects size (LEfSe) detected 27 differentially abundant bacterial taxa (a= 0.01, LDA score >2.0). While Gammaproteobacteria was overrepresented, Erysipelotrichia, Clo.....
    Document: Ten diabetic dogs and 10 healthy controls were enrolled. Fecal microbial diversity was lower in DM dogs when compared to healthy controls. PCA based on unweighted Unifrac distance metric did not reveal significant clustering between dog groups. However, linear discriminate analysis effects size (LEfSe) detected 27 differentially abundant bacterial taxa (a= 0.01, LDA score >2.0). While Gammaproteobacteria was overrepresented, Erysipelotrichia, Clostridia, and Bacteroidia were underrepresented in DM dogs compared to healthy controls (P < 0.05 for all). Total primary BA were increased in DM dogs compared with healthy controls (P = 0.03) and lithocholic acid was decreased (P < 0.05) in dogs with DM.

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