Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018 Document date: 2018_10_25
ID: 60ceejq1_521
Snippet: In conclusion, feline CKD is associated with decreased diversity of the gut microbiome. IS is significantly elevated in feline CKD and merits exploration as a potential therapeutic target. Additionally, IRIS stage 2 cats may suffer from a similar uremic toxin burden as cats with later stage disease. Additional work is needed to further understand the interplay between the fecal microbiome and uremic toxins. Twenty percent of cats (n = 12) were ex.....
Document: In conclusion, feline CKD is associated with decreased diversity of the gut microbiome. IS is significantly elevated in feline CKD and merits exploration as a potential therapeutic target. Additionally, IRIS stage 2 cats may suffer from a similar uremic toxin burden as cats with later stage disease. Additional work is needed to further understand the interplay between the fecal microbiome and uremic toxins. Twenty percent of cats (n = 12) were excluded due to a urinary tract infection (UTI) at presentation. The mean SDMA and creatinine were significantly higher in these cats (59.6 μg/dL and 11.7 mg/dL, respectively), compared with those without a UTI (27.6 μg/dL and 4.76 mg/dL, respectively) (p < 0.002, < 0.001).
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