2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

The fecal score did not differ significantly between the 2 groups at either T0 or at T2 (p = 0.200 and p = 0.116, respectively). At T3, the FMT group had a significantly lower fecal score than the MTZ group (p = 0.020). DI did not differ significantly at T0 between the two groups (p = 0.961). At T2 and T3, the FMT group had a significantly lower DI than the MTZ groups (p = 0.001 and p = 0.002, respectively). Recovery from dysbiosis was also evaluated, and the FMT group had a significantly lower rate of dysbiosis (30% [3/10] Fat-loading resulted in significantly longer gastric transit times when compared to controls (p < 0.01). Also, gastric retention of the capsules occurred significantly more commonly in dogs fed either corn oil or dairy cream (p < 0.01). While 10/16 fat-loading studies resulted in gastric retention of the capsule for more than 12 hours, none of the control studies had gastric retention. In addition, gastric retention occurred significantly more often with dogs fed corn oil than dairy cream (p < 0.05). Though gastric retention limited the number of cases where visual assessment of the small intestinal mucosa could be performed, 5/6 fat-loaded studies were subjectively judged to have moderate to marked prominence of villi with increased numbers of dilated lacteals when compared to control studies.