Selected article for: "arachidonic acid and AUC curve area"

Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018
  • Document date: 2018_10_25
  • ID: 60ceejq1_430
    Snippet: Therefore, the purpose of this study was to determine the viability of reconstituted arachidonic acid (AA) and adenosine diphosphate (ADP) platelet agonists stored under two conditions up to 6 months. 60μl aliquots of reconstituted AA and ADP were stored at -20 C and -80 C monthly for six months. Six healthy staff-owned dogs were enrolled for the study. A physical examination, complete blood count (CBC), diagnostic panel, and urinalysis were per.....
    Document: Therefore, the purpose of this study was to determine the viability of reconstituted arachidonic acid (AA) and adenosine diphosphate (ADP) platelet agonists stored under two conditions up to 6 months. 60μl aliquots of reconstituted AA and ADP were stored at -20 C and -80 C monthly for six months. Six healthy staff-owned dogs were enrolled for the study. A physical examination, complete blood count (CBC), diagnostic panel, and urinalysis were performed in all enrolled dogs. Platelet aggregometry was performed on all dogs using fresh and stored aliquots of AA and ADP reagents on the same day. The area under the curve (AUC) was recorded from each platelet aggregometry analysis. Repeated measures (RM) analysis (one-way ANOVA) was performed and subsequent time points (1, 2, 3, 4, 5, 6 months) were compared to fresh AUC results.

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