Bronchiolitis needs a revisit: Distinguishing between virus entities and their treatments

Jartti, Tuomas; Smits, Hermelijn H.; Bønnelykke, Klaus; Bircan, Ozlem; Elenius, Varpu; Konradsen, Jon R.; Maggina, Paraskevi; Makrinioti, Heidi; Stokholm, Jakob; Hedlin, Gunilla; Papadopoulos, Nikolaos; Ruszczynski, Marek; Ryczaj, Klaudia; Schaub, Bianca; Schwarze, Jürgen; Skevaki, Chrysanthi; Stenberg-Hammar, Katarina; Feleszko, Wojciech

Maternal omega-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) and vitamin D supplementation in the third trimester of pregnancy may reduce the risk of persistent wheeze/asthma and respiratory infections in offspring ( Figure 5 ). 93, 94 Secondary prevention strategies of asthma aim at avoiding the development of allergic disease/asthma in already sensitized or wheezing subjects. 95 Thus far, allergen immunotherapy remains as the only treatment available for modifying the course of allergic disease. 96 However, although in a recent study grass pollen immunotherapy was shown to reduce asthma-like symptoms in children, it did not decrease the development of asthma. 97 Interestingly, though, a systemic anti-inflammatory treatment of the first RV-induced severe wheezing episode markedly decreased the subsequent risk of asthma ( Figure 5) , (see section 7). [74] [75] [76] [77] Also, a