Author: McWhirter, Sarah M.; Barbalat, Roman; Monroe, Kathryn M.; Fontana, Mary F.; Hyodo, Mamoru; Joncker, Nathalie T.; Ishii, Ken J.; Akira, Shizuo; Colonna, Marco; Chen, Zhijian J.; Fitzgerald, Katherine A.; Hayakawa, Yoshihiro; Vance, Russell E.
Title: A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP Document date: 2009_8_31
ID: 3b8b8p61_23
Snippet: Our genetic data suggested that the cytosolic responses to DNA, RNA, and c-di-GMP share a common downstream signaling pathway. If this were true, we would expect to be able to detect biochemical activation of the NF-î«B and IRF3.....
Document: Our genetic data suggested that the cytosolic responses to DNA, RNA, and c-di-GMP share a common downstream signaling pathway. If this were true, we would expect to be able to detect biochemical activation of the NF-î«B and IRF3
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