Author: Yu, Chenglong; Liang, Qian; Yin, Changchuan; He, Rong L.; Yau, Stephen S.-T.
Title: A Novel Construction of Genome Space with Biological Geometry Document date: 2010_4_1
ID: 3c4dttrt_6
Snippet: Here, we should emphasize that the specific ordering of the four nucleotides in the Cartesian coordinate system is related to the GC content of genomes (as it is explained in the 'Discussion' section). Points in the graphical representation are obtained by the sum of vectors representing nucleotides in the sequence. In Fig. 2 , we give the graphical representation of whole mitochondrial genome sequences of human, common chimpanzee, Norway rat, an.....
Document: Here, we should emphasize that the specific ordering of the four nucleotides in the Cartesian coordinate system is related to the GC content of genomes (as it is explained in the 'Discussion' section). Points in the graphical representation are obtained by the sum of vectors representing nucleotides in the sequence. In Fig. 2 , we give the graphical representation of whole mitochondrial genome sequences of human, common chimpanzee, Norway rat, and hedgehog, which are based on the vector system shown in Fig. 1 . Since human and chimpanzee belong to the same order ( primates), their mitochondrial genome graphical representations are very similar visually. These four DNA sequence graphical curves have no circuits or degeneracy and the correspondence between the sequence and the graphical curve can be mathematically proved to be one-to-one. 9
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