Author: Folarin, Onikepe A.; Ehichioya, Deborah; Schaffner, Stephen F.; Winnicki, Sarah M.; Wohl, Shirlee; Eromon, Philomena; West, Kendra L.; Gladden-Young, Adrianne; Oyejide, Nicholas E.; Matranga, Christian B.; Deme, Awa Bineta; James, Ayorinde; Tomkins-Tinch, Christopher; Onyewurunwa, Kenneth; Ladner, Jason T.; Palacios, Gustavo; Nosamiefan, Iguosadolo; Andersen, Kristian G.; Omilabu, Sunday; Park, Daniel J.; Yozwiak, Nathan L.; Nasidi, Abdusallam; Garry, Robert F.; Tomori, Oyewale; Sabeti, Pardis C.; Happi, Christian T.
Title: Ebola Virus Epidemiology and Evolution in Nigeria Document date: 2016_10_15
ID: 2g9ggwog_39
Snippet: The close proximity of the sample collection dates to each other suggests that each of the corresponding case patients was infected by the index case patient (ie, it is unlikely that an individual presenting symptoms on 8 August 2014 would have been infected <4 days previously) [24] . The remaining 2 cases with viral genomes identical to the index case are dated 15 August and 1 September, and these patients therefore may have been infected by 1 o.....
Document: The close proximity of the sample collection dates to each other suggests that each of the corresponding case patients was infected by the index case patient (ie, it is unlikely that an individual presenting symptoms on 8 August 2014 would have been infected <4 days previously) [24] . The remaining 2 cases with viral genomes identical to the index case are dated 15 August and 1 September, and these patients therefore may have been infected by 1 of the earlier case patients. The presence of additional SNPs in the viral genomes corresponding to cases 2 and 9 make it difficult to place these samples within the transmission chain. However, case 6 has an iSNV at each of the 2 case 9 SNP positions (position 7551, 21% minor allele frequency; position 10 503, 16% minor allele frequency) (Supplementary Data 2), suggesting that these 2 cases are closely linked.
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