Author: Lee, Hyojin; Kim, Eun-Ju; Song, Jae-Young; Choi, Jeong Soo; Lee, Ji Youn; Cho, In-Soo; Shin, Yeun-Kyung
Title: Development and evaluation of a competitive enzyme-linked immunosorbent assay using a monoclonal antibody for diagnosis of severe fever with thrombocytopenia syndrome virus in bovine sera Document date: 2016_9_20
ID: 0pe8vgin_1
Snippet: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-mediated infectious disease that was recently discovered in the rural areas of China [24] . The clinical characteristics of this disease in humans primarily include thrombocytopenia, leukocytopenia, high fever, gastrointestinal symptoms, and imbalanced liver enzyme production [21] . The pathogen responsible for SFTS is the SFTS virus (SFTSV), a novel Phlebovirus in the family .....
Document: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-mediated infectious disease that was recently discovered in the rural areas of China [24] . The clinical characteristics of this disease in humans primarily include thrombocytopenia, leukocytopenia, high fever, gastrointestinal symptoms, and imbalanced liver enzyme production [21] . The pathogen responsible for SFTS is the SFTS virus (SFTSV), a novel Phlebovirus in the family Bunyaviridae [21] . This virus contains three RNA genome segments coated with nucleoprotein (NP) that are encapsulated in an 80-to 120 nm diameter glycoprotein viral envelope [21, 24] . Since the first report of human SFTS in central China, additional cases have been reported continuously in other parts of China, Korea, and Japan [17, 25, 26] . In 2013, 36 patients were diagnosed with SFTS, and the fatality rate of this disease was 47.2% in Korea [6, 12] .
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