Author: Song, Jae-Hyoung; Shim, Aeri; Kim, Yeon-Jeong; Ahn, Jae-Hee; Kwon, Bo-Eun; Pham, Thuy Trang; Lee, Jongkook; Chang, Sun-Young; Ko, Hyun-Jeong
Title: Antiviral and Anti-Inflammatory Activities of Pochonin D, a Heat Shock Protein 90 Inhibitor, against Rhinovirus Infection Document date: 2018_5_2
ID: 0bwf8f1i_22
Snippet: To evaluate the effect of pochonin D on lung histology in HRV1B-infected mice, we dissected the lung tissue and performed histological analysis as reported previously (Ahn et al., 2008) . Briefly, lung tissues were fixed in 4% formaldehyde (Masked Formalin, DANA Korea, Incheon, Korea), dehydrated in graded concentrations of ethanol, washed in xylene, and embedded in paraffin. Paraffin blocks were sliced to obtain 10-μm-thick sections, which were.....
Document: To evaluate the effect of pochonin D on lung histology in HRV1B-infected mice, we dissected the lung tissue and performed histological analysis as reported previously (Ahn et al., 2008) . Briefly, lung tissues were fixed in 4% formaldehyde (Masked Formalin, DANA Korea, Incheon, Korea), dehydrated in graded concentrations of ethanol, washed in xylene, and embedded in paraffin. Paraffin blocks were sliced to obtain 10-μm-thick sections, which were then stained with hematoxylin and eosin (H&E). The sections were observed by a pathologist in a blind test under a light microscope. Each sample was scored based on the extent of edema, hemorrhage, and cell infiltration.
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