Clinical Features and Radiological Findings of Adenovirus Pneumonia Associated with Progression to Acute Respiratory Distress Syndrome: A Single Center Study in 19 Adult Patients

Cha, Min Jae; Chung, Myung Jin; Lee, Kyung Soo; Kim, Tae Jung; Kim, Tae Sung; Chong, Semin; Han, Jungho

Two chest radiologists (MJC and MJJ, with five and 22 years of experience in chest imaging interpretation, respectively) assessed chest radiographs and CT images; decisions were reached by consensus. The abnormalities on initial chest radiographs were assessed as focal opacity or multifocal or diffuse opacity (15) . Parenchymal opacity was defined as an area that appears denser than the surrounding lung tissue without a discrete border. The pattern of the disease course was also identified from sequential chest radiographs as described by Wong et al. (16) and Das et al. (17) , where type 1 was radiographic improvement, type 2 was radiographic deterioration by one peak level followed by improvement, type 3 was fluctuating radiographic changes with at least two peaks, and type 4 was progressive radiographic deterioration. Peak level was defined as overall lung parenchymal involvement greater than 25% of the initial extent on radiography.