Clinical Features and Radiological Findings of Adenovirus Pneumonia Associated with Progression to Acute Respiratory Distress Syndrome: A Single Center Study in 19 Adult Patients

Cha, Min Jae; Chung, Myung Jin; Lee, Kyung Soo; Kim, Tae Jung; Kim, Tae Sung; Chong, Semin; Han, Jungho

Patterns and distribution of CT findings are summarized in Table 2 . The most frequent CT appearance was GGO, which was seen in all patients (n = 19), combined with other patterns such as consolidation (n = 14) and micronodules (n = 3). Parenchymal abnormalities were distributed bilaterally in 17 patients (Figs. 1, 2) , whereas unilateral involvement was seen in two patients (Fig. 3) . Interlobular septal thickening was demonstrated in 12 patients, and pleural effusion was present in 11 patients. The average number of lobes involved was 4.2 ± 1.4 (range, 1 to 5). Pulmonary abnormalities showed upper lung zone predominance in four patients (21%) and lower lung zone predominance in six patients (32%). However, nine patients (47%) showed random parenchymal involvement without zonal predominance. In terms of axial distribution, most of the cases (79%) showed mixed central and peripheral involvement. Table 3 shows the comparison between the ARDS and non-ARDS groups according to clinical and radiological findings. No significant differences between the groups were identified for the clinical variables of patient age (p = 0.651), sex (p = 0.998), or presence of premorbid A B Fig. 1. 20 -year-old immunocompetent man complaining of fever, dyspnea, productive cough, and sputum.