Author: GASPARINI, R.; AMICIZIA, D.; LAI, PL.; BRAGAZZI, NL.; PANATTO, D.
Title: Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part I: influenza life-cycle and currently available drugs Document date: 2014_9_23
ID: 5td3lhlf_16
Snippet: The next event in replication is the importation of RNP into the nucleus. The trafficking of RNP into the cytoplasm is achieved extremely rapidly, by means of a mechanism of diffusion, without the intervention of microtubules, intermediate filaments or actin filaments, through the nuclear pore complex (NPC). Some important components of the NPC are the nucleoporins Nup37, Nup43, Nup45 [128] , Nup50 [129] , Nup54 [130] , Nup58 [128] , Nup62 [131] .....
Document: The next event in replication is the importation of RNP into the nucleus. The trafficking of RNP into the cytoplasm is achieved extremely rapidly, by means of a mechanism of diffusion, without the intervention of microtubules, intermediate filaments or actin filaments, through the nuclear pore complex (NPC). Some important components of the NPC are the nucleoporins Nup37, Nup43, Nup45 [128] , Nup50 [129] , Nup54 [130] , Nup58 [128] , Nup62 [131] , Nup75, Nup88, Nup93, Nup98, Nup107, Nup133 [128] , Nup153 [132] [133] [134] [135] , Nup160 [128] , Nup214 [130] , NuTF2 (Nuclear Transport Factor 2) and Nup358/RanBP2 [128] .
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