Selected article for: "apoptotic death and cell response"
Author: Kim, Sang Chan; Park, Sook Jahr; Lee, Jong Rok; Seo, Jung Cheol; Yang, Chae Ha; Byun, Sung Hui
Title: Cytoprotective Activity of Glycyrrhizae radix Extract Against Arsenite-induced Cytotoxicity
  • Document date: 2007_3_25
    • ID: 0c5p8sjk_25
    Snippet: To investigate whether cell death observed in response to As was apoptosis, cells were analyzed using a flow cytometer. As shown in Fig. 4 , As-induced apoptotic cell death showed that a larger apoptotic population of cells was increased in the As-treated group compared with the control group (7.93% versus 0.73%). In contrast, licorice prevented As-induced apoptotic cell death, with 1.0 mg ml À1 of licorice reducing the apoptotic population to o.....
    Document: To investigate whether cell death observed in response to As was apoptosis, cells were analyzed using a flow cytometer. As shown in Fig. 4 , As-induced apoptotic cell death showed that a larger apoptotic population of cells was increased in the As-treated group compared with the control group (7.93% versus 0.73%). In contrast, licorice prevented As-induced apoptotic cell death, with 1.0 mg ml À1 of licorice reducing the apoptotic population to only 1.73%. Our previous study showed that licorice prevented Cd-induced cell death in H4IIE cells (3) . Taken together, these results provided strong evidence that licorice effectively inhibits Cd-or As-induced cytotoxicity.

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