Author: Hayden C. Metsky; Katherine J. Siddle; Adrianne Gladden-Young; James Qu; David K. Yang; Patrick Brehio; Andrew Goldfarb; Anne Piantadosi; Shirlee Wohl; Amber Carter; Aaron E. Lin; Kayla G. Barnes; Damien C. Tully; Björn Corleis; Scott Hennigan; Giselle Barbosa-Lima; Yasmine R. Vieira; Lauren M. Paul; Amanda L. Tan; Kimberly F. Garcia; Leda A. Parham; Ikponmwonsa Odia; Philomena Eromon; Onikepe A. Folarin; Augustine Goba; Etienne Simon-Lorière; Lisa Hensley; Angel Balmaseda; Eva Harris; Douglas Kwon; Todd M. Allen; Jonathan A. Runstadler; Sandra Smole; Fernando A. Bozza; Thiago M. L. Souza; Sharon Isern; Scott F. Michael; Ivette Lorenzana; Lee Gehrke; Irene Bosch; Gregory Ebel; Donald Grant; Christian Happi; Daniel J. Park; Andreas Gnirke; Pardis C. Sabeti; Christian B. Matranga
Title: Capturing diverse microbial sequence with comprehensive and scalable probe design Document date: 2018_3_12
ID: a9lkhayg_39
Snippet: CATCH is, to our knowledge, the first approach to systematically design probe sets for whole genome capture of highly diverse target sequences that span many species. Our results show that it offers an important extension to the field's toolkit for effective viral detection and surveillance with enrichment and other targeted approaches. We anticipate that CATCH, together with these approaches, will help provide a more complete understanding of ge.....
Document: CATCH is, to our knowledge, the first approach to systematically design probe sets for whole genome capture of highly diverse target sequences that span many species. Our results show that it offers an important extension to the field's toolkit for effective viral detection and surveillance with enrichment and other targeted approaches. We anticipate that CATCH, together with these approaches, will help provide a more complete understanding of genetic diversity across the microbial world.
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