Author: Kim, Sang Chan; Park, Sook Jahr; Lee, Jong Rok; Seo, Jung Cheol; Yang, Chae Ha; Byun, Sung Hui
Title: Cytoprotective Activity of Glycyrrhizae radix Extract Against Arsenite-induced Cytotoxicity Document date: 2007_3_25
ID: 0c5p8sjk_29
Snippet: In this study, we focused on the cytoprotective effects of licorice against As-induced cytotoxicity. We revealed that licorice was capable of blocking As-induced apoptotic cell death, and that, in particular, licorice pre-treatment prevented the subsequent As-induced cytotoxicity. Incubation of cells with licorice alone at the concentration of 1.0 mg ml À1 for 12-24 h increased cell proliferation (4) , suggesting that the cellular protein(s) res.....
Document: In this study, we focused on the cytoprotective effects of licorice against As-induced cytotoxicity. We revealed that licorice was capable of blocking As-induced apoptotic cell death, and that, in particular, licorice pre-treatment prevented the subsequent As-induced cytotoxicity. Incubation of cells with licorice alone at the concentration of 1.0 mg ml À1 for 12-24 h increased cell proliferation (4) , suggesting that the cellular protein(s) responsible for cell survival is (are) activated by the components in licorice, which may also be associated with its cytoprotective effect against As-induced cell injury.
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