Selected article for: "DMSO control and vehicle DMSO control"
Author: Ross D. Overacker; Somdev Banerjee; George F. Neuhaus; Selena Milicevic Sephton; Alexander Herrmann; James A. Strother; Ruth Brack-Werner; Paul R. Blakemore; Sandra Loesgen
Title: Biological Evaluation of Molecules of the azaBINOL Class as Antiviral Agents: Specific Inhibition of HIV-1 RNase H Activity by 7-Isopropoxy-8-(naphth-1-yl)quinoline
  • Document date: 2019_1_23
    • ID: m2zw8eq4_40
    Snippet: To gain a further understanding of the mechanism of action of the antiviral azaBINOL The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/525105 doi: bioRxiv preprint Antiviral azaBINOL B#24 was assessed for inhibition of HIV-1 reverse transcriptase using a 511 commercially available colorimetric reverse transcriptase assay kit (Roche) according to the 512 manufacturer's instructions.....
    Document: To gain a further understanding of the mechanism of action of the antiviral azaBINOL The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/525105 doi: bioRxiv preprint Antiviral azaBINOL B#24 was assessed for inhibition of HIV-1 reverse transcriptase using a 511 commercially available colorimetric reverse transcriptase assay kit (Roche) according to the 512 manufacturer's instructions. IC50 values were determined through a dilution series run in 513 triplicate. Normalized percentages of inhibitory activity were calculated using positive and 514 negative control wells with a set amount of vehicle solvent (10% DMSO). 515

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