Title: Enhancement of IgE-mediated histamine release from human basophils by viruses: role of interferon Document date: 1977_4_1
ID: 5v7k90zr_19
Snippet: To determine the minimum length of time between exposure of leukocytes to virus and development of enhanced histamine release, leukocytes were exposed to UV-inactivated HSV-1 for 2 h. The viral inoculum was removed and the cells were washed and incubated at 37°C. At 4, 8, 16, 24 , and 48 h after initial exposure to virus, the leukocytes were challenged with anti-IgE. The data in Fig. 4 show significant enhancement of histamine release beginning .....
Document: To determine the minimum length of time between exposure of leukocytes to virus and development of enhanced histamine release, leukocytes were exposed to UV-inactivated HSV-1 for 2 h. The viral inoculum was removed and the cells were washed and incubated at 37°C. At 4, 8, 16, 24 , and 48 h after initial exposure to virus, the leukocytes were challenged with anti-IgE. The data in Fig. 4 show significant enhancement of histamine release beginning at 8 h after exposure of cells to virus (P < 0.001). This effect increased progressively up to 48 h.
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