Selected article for: "international license and synaptic vesicle"
Author: Monika Litvinukova; Carlos Talavera-Lopez; Henrike Maatz; Daniel Reichart; Catherine L. Worth; Eric L. Lindberg; Masatoshi Kanda; Krzysztof Polanski; Eirini S. Fasouli; Sara Samari; Kenny Roberts; Elizabeth Tuck; Matthias Heinig; Daniel DeLaughter; Barbara McDonough; Hiroko Wakimoto; Joshua M. Gorham; Emily Nadelmann; Krishnaa T. Mahbubani; Kourosh Saeb-Parsy; Giannino Patone; Joseph J Boyle; Hongbo Zhang; Hao Zhang; Anissa Viveiros; Gavin Oudit; Omer Bayraktar; J. G. Seidman; Christine Seidman; Michela Noseda; Norbert Hubner; Sarah A. Teichmann
Title: Cells and gene expression programs in the adult human heart
  • Document date: 2020_4_5
    • ID: 1ilforzm_11
    Snippet: . CC-BY-NC 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.024075 doi: bioRxiv preprint The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.024075 doi: bioRxiv preprint bottom) denoting age, circulatory perfusion before tissue isolation (black drop sign).....
    Document: . CC-BY-NC 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.024075 doi: bioRxiv preprint The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.024075 doi: bioRxiv preprint bottom) denoting age, circulatory perfusion before tissue isolation (black drop sign), and donors providing both cells and nuclei (orange circle) C. UMAP depiction of transcriptional data from cells and nuclei that identified ten cardiac cell types cardiac tissues studied. D. Table B1 ), including HCN1 , MYH6 , MYL4 and NPPA . In addition, we identified a higher aCM expression of ALDH1A2 (9-fold increased), the catalytic enzyme required for synthesis of retinoic acid, that may reflect aCM derived from the second heart field 9 . aCM also showed higher levels of ROR2 (22-fold increased), which participates in cardiomyocyte differentiation via Wnt-signaling, as well as SYNPR (29-fold increased), a synaptic vesicle membrane protein with functions in TRP-channel mechanosensing by atrial volume receptors 10 , 11 .

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