Author: Baek, Hyekyung; Kim, Kwang Ho; Park, Min Young; Kim, Kyeongryun; Ko, Bokyeong; Seo, Hyung Seok; Kim, Byoung Soo; Hahn, Tae-Wook; Yi, Sun Shin
Title: Establishment of minimal positive-control conditions to ensure brain safety during rapid development of emergency vaccines Document date: 2017_8_22
ID: 52sbckm3_16
Snippet: The permeability of EB dye into brain parenchymal tissue after LPS injection is presented as a ratio of the EB dye amount in brain to that in blood (Fig. 1) . When LPS was injected into mice, EB penetrance increased, regardless of the LPS source. However, between the two different mouse strains, the EB ratio was significantly higher in ICR mice than in B6 mice. Interestingly, the LPS(S)-injected group showed a greater increase in EB ratio than th.....
Document: The permeability of EB dye into brain parenchymal tissue after LPS injection is presented as a ratio of the EB dye amount in brain to that in blood (Fig. 1) . When LPS was injected into mice, EB penetrance increased, regardless of the LPS source. However, between the two different mouse strains, the EB ratio was significantly higher in ICR mice than in B6 mice. Interestingly, the LPS(S)-injected group showed a greater increase in EB ratio than that in the LPS(E)-injected group and that tendency was significant in ICR mice.
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