Author: Won, Hokeun; Lee, Dong-Uk; Jang, Guehwan; Noh, Yun-Hee; Lee, Seung-Chul; Choi, Hwan-Won; Yoon, In-Joong; Yoo, Han Sang; Lee, Changhee
Title: Generation and protective efficacy of a cold-adapted attenuated genotype 2b porcine epidemic diarrhea virus Document date: 2019_7_9
ID: 2hxlx1j2_41
Snippet: To evaluate the protective effectiveness of a cold-adapted PEDV vaccine, our study employed an oral homologous prime-boost vaccination scheme at 2 weeks apart before farrowing. Three sows in group 1 were orally primed and boosted with live vaccines at 4 and 2 weeks pre-partum, whereas 2 positive (group 2) and 1 negative (group 3) control animals were kept Clinical significance score Log TCID /mL unvaccinated. All sows in the vaccinated and unvacc.....
Document: To evaluate the protective effectiveness of a cold-adapted PEDV vaccine, our study employed an oral homologous prime-boost vaccination scheme at 2 weeks apart before farrowing. Three sows in group 1 were orally primed and boosted with live vaccines at 4 and 2 weeks pre-partum, whereas 2 positive (group 2) and 1 negative (group 3) control animals were kept Clinical significance score Log TCID /mL unvaccinated. All sows in the vaccinated and unvaccinated groups experienced neither PEDlike clinical symptoms, including PEDV fecal shedding, nor adverse reactions to vaccines. At farrowing, there were no significant differences in reproductive performance between the vaccinated and unvaccinated sows.
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