Highly sensitive simultaneous electrochemical determination of myricetin and rutin via solid phase extraction on a ternary Pt@r-GO@MWCNTs nanocomposite

Tursynbolat, Satar; Bakytkarim, Yrysgul; Huang, Jianzhi; Wang, Lishi

To date, some analytical methods have been developed to simultaneously detect myricetin and rutin, including capillary electrophoresis [4, 5] , chemiluminescence [6] , high performance liquid chromatography (HPLC) [7] , and spectrophotometry [8] . These methods can sensitively detect myricetin and rutin, but they have many drawbacks including the need for expensive equipment and time-consuming experimental processes, which constrain their practical application [9e18] . Compared to previously developed methods, voltammetry provides a fast response, uses simple equipment, and is highly sensitive to the determination of myricetin or rutin [19e28] . Although many electrochemical sensors have been reported for single determinations of myricetin or rutin [29e35], their simultaneous determination has seldom been reported due to their analogous chemical structures and electrochemical characteristics, resulting in an indistinguishable potential [36, 37] . Therefore, it is imperative to develop an electrochemical sensor that can realize the simultaneous determination of myricetin and rutin.