Author: Ivanova, Elena; Berger, Audrey; Scherrer, Anne; Alkalaeva, Elena; Strub, Katharina
Title: Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits Document date: 2015_3_11
ID: 64cnoqpi_73
Snippet: This study introduces a novel concept that a noncoding RNA shuttles an RNA-binding protein to its functional binding site on a large molecular complex thereby regulating its activity. It is conceivable that this concept is not restricted to translational control but is applicable to a multitude of cellular processes and more examples of RNAmediated protein delivery might be discovered in the future......
Document: This study introduces a novel concept that a noncoding RNA shuttles an RNA-binding protein to its functional binding site on a large molecular complex thereby regulating its activity. It is conceivable that this concept is not restricted to translational control but is applicable to a multitude of cellular processes and more examples of RNAmediated protein delivery might be discovered in the future.
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