Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_867
Snippet: Six groups were defined: 1.) thermogel, 2.) 1 mg voriconazole + thermogel, 3.) 1 mg voriconazole in ethanol + thermogel, 4.) 5 mg voriconazole + thermogel, 5.) 5 mg voriconazole in ethanol + thermogel and 6.) 5 mg voriconazole. Thermogel samples were maintained at 34.5°C in phosphate buffered saline (PBS). PBS was collected daily for 28 days and voriconazole concentrations determined via high-performance liquid chromatography. Ten normothermic e.....
Document: Six groups were defined: 1.) thermogel, 2.) 1 mg voriconazole + thermogel, 3.) 1 mg voriconazole in ethanol + thermogel, 4.) 5 mg voriconazole + thermogel, 5.) 5 mg voriconazole in ethanol + thermogel and 6.) 5 mg voriconazole. Thermogel samples were maintained at 34.5°C in phosphate buffered saline (PBS). PBS was collected daily for 28 days and voriconazole concentrations determined via high-performance liquid chromatography. Ten normothermic ex vivo horse eyes were injected with 300 lL thermogel and evaluated via high-resolution (50 MHz) ultrasound.
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