2016 ACVIM Forum Research Abstract Program

These results suggest that macrophages may play a role in canine CE. Further characterization of macrophages is warranted to understand their role in CE. The term protein-losing enteropathy (PLE) is often applied to cases of chronic enteropathy (CE) when the disease process results in hypoalbuminemia. Multiple previous studies have identified hypoalbuminemia as a risk factor for a negative outcome in dogs with chronic enteropathy, yet it has not been determined whether the histopathology differs between CE dogs with and without hypoalbuminemia. The goal of this retrospective study was to compare histopathologic findings (as determined by the WSAVA scoring system) in dogs with CE with and without hypoalbuminemia.