Author: Won, Hokeun; Lee, Dong-Uk; Jang, Guehwan; Noh, Yun-Hee; Lee, Seung-Chul; Choi, Hwan-Won; Yoon, In-Joong; Yoo, Han Sang; Lee, Changhee
Title: Generation and protective efficacy of a cold-adapted attenuated genotype 2b porcine epidemic diarrhea virus Document date: 2019_7_9
ID: 2hxlx1j2_18
Snippet: To assess immunogenicity of cold-adapted derivatives, a total of 14 3-week-old conventional piglets delivered from commercial crossbred sows (Great Yorkshire × Dutch Landrace) were allocated into the cold adapted Aram-P29-CA-inoculated (n = 3), P33-CA-inoculated (n = 3), P-45-CA-inoculated (n = 3), P50-CA-inoculated (n = 3), and sham-inoculated control (n = 2) groups. Animals were immunized orally with a 1 mL dose of 10 4.5 TCID 50 /mL of each v.....
Document: To assess immunogenicity of cold-adapted derivatives, a total of 14 3-week-old conventional piglets delivered from commercial crossbred sows (Great Yorkshire × Dutch Landrace) were allocated into the cold adapted Aram-P29-CA-inoculated (n = 3), P33-CA-inoculated (n = 3), P-45-CA-inoculated (n = 3), P50-CA-inoculated (n = 3), and sham-inoculated control (n = 2) groups. Animals were immunized orally with a 1 mL dose of 10 4.5 TCID 50 /mL of each virus or sham inoculated with cell culture medium. Pre-immune sera were collected at the immunization, and antisera were collected at 1 week intervals for 3 weeks.
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